The Interplay Between High Uric Acid, Psychological Symptoms, and How to Lower Your Levels: A Dietary and Supplement Guide

When it comes to maintaining good health, most people focus on obvious aspects like a balanced diet, regular exercise, or maintaining healthy weight. However, there's a lesser-known player in the overall health game, and that's uric acid. A waste product that's produced when the body breaks down purines (substances in certain foods and our cells), uric acid is usually expelled by the kidneys. But when produced excessively or not adequately eliminated, uric acid levels can surge, leading to problems such as gout and kidney stones.

More surprisingly, recent research suggests that elevated uric acid levels may also be linked with psychological symptoms. Understanding this connection, and knowing how to manage uric acid levels, can provide a more comprehensive approach to mental health care.

High Uric Acid and Psychological Health

Research indicates that high uric acid levels could correlate with mental health disorders such as depression, anxiety, bipolar disorder, and schizophrenia. A study in the Journal of Affective Disorders discovered a significant link between high uric acid and major depressive disorder, particularly in women.

Additionally, elevated uric acid levels have been observed during manic episodes in patients with bipolar disorder. Meanwhile, the Journal of Psychiatric Research has published findings suggesting a positive correlation between high uric acid levels and the severity of schizophrenia.

Although these findings are preliminary and the biological mechanisms are not fully understood, it's clear that high uric acid levels may contribute to certain mental health conditions, either by exacerbating existing symptoms or potentially triggering new ones.

Reducing Uric Acid Levels: Dietary Changes, Supplements, and A Helpful Book


Controlling uric acid levels involves lifestyle changes, especially in diet, which can not only help maintain physical health but also potentially improve mental well-being.

Dietary changes: Reduce consumption of purine-rich foods like red meat, organ meats, seafood, and alcoholic beverages. Instead, incorporate more low-purine foods such as fruits, vegetables, whole grains, and lean proteins into your diet.

Stay hydrated: Drink plenty of water to help your kidneys efficiently remove uric acid.

Achieve and maintain a healthy weight: High uric acid levels are often associated with obesity. Regular exercise and balanced dieting can help.

Limit alcohol and fructose-sweetened drinks: These can spike uric acid levels.

Consider Supplements: Certain natural supplements have been shown to support the lowering of uric acid levels. These include Vitamin C, which may help reduce uric acid in the blood, and Cherries or cherry extract, known to decrease uric acid levels and reduce gout flare-ups. Always consult with a healthcare provider before starting any supplement regimen.

Explore Helpful Literature: If you're looking for a comprehensive guide to a low uric acid diet, consider purchasing the book "Beating Gout: A Sufferer's Guide to Living Pain Free" by Victor Konshin. This practical guide offers a wealth of information about uric acid, its health impacts, and how dietary changes can help manage uric acid levels.

Medication: In some cases, medication might be necessary. Consult with a healthcare provider before starting any new medication.


The research connecting high uric acid levels and psychological symptoms offers a new perspective on holistic health management. Although we are still learning about this complex relationship, awareness of this link allows for early intervention and potential improvements in patient outcomes.

By adopting lifestyle changes that lower uric acid levels, we are not just averting physical conditions like gout or kidney stones. We could also be taking important steps towards better mental health.

Remember to always consult a healthcare provider if you're experiencing psychological symptoms or if you have concerns about uric acid levels. And most importantly, realize that your physical health and mental health are intertwined—taking care of your body is a vital part of taking care of your mind.